You can get the new Microsoft Edge for Windows and macOS today by downloading it directly from microsoft.com/edge. When you install Microsoft Edge on an up-to-date Windows 10 device, it will replace the previous (legacy) version on your device. In some cases, you may be prompted to install additional updates. Your favorites, passwords, and basic settings will carry over to the new Microsoft Edge automatically. Web apps (including those built on EdgeHTML), and Microsoft Edge preview channels (such as Dev or Canary) will continue to work without interruption.
! Chromium Edge v79.0
If you aren't allowed to use any web browsers, then your requirement will not be possible to achieve. If you can use any chromium-based web browser such as Microsoft Edge or Google chrome. If you use anything other than google chrome, then you will have to change the config file.
Download web installer: Google Chrome Web 32-bit Google Chrome 64-bit FreewareDownload: Google Chrome Offline Installer 32-bit 54.8 MBDownload: Google Chrome Offline Installer 64-bit 55.8 MBDownload: Google Chrome MSI Installers for Windows (automatic update)View: Chrome Website v79.0.3945.130 Release Notes
In a study of postnatal development and behaviour after prenatal exposure, 21 CD1 mice were exposed throughout gestation to a sinusoidal 50-Hz, 20-mT magnetic field. Three possibly field-dependent effects were noted: exposed animals performed the air-righting reflex about two days earlier than controls; exposed males weighed significantly less than controls at 30 days of age; and exposed animals remained on a Rota-rod for less time as juveniles than sham-exposed control mice (n = 23). No field-dependent effect on the surface-righting reflex or eye opening was reported, in contrast to the findings of Zusman et al. (1990) (see above). There was a suggestion that exposed animals took slightly longer to avoid a cliff edge, but this difference was of borderline significance. In the activity wheel, a slightly increased activity of exposed females and a slightly decreased activity of exposed males was noted compared with control mice, but these effects were not considered by the authors to be of any biological significance. The reduction in running time on a Rota-rod, observed in juvenile mice, may represent an impairment of motor coordination during adolescence induced by the magnetic field. No gross impairments of postnatal development or behaviour were seen in the exposed mice (Sienkiewicz et al., 1994).
Murine cytotoxic T-lymphocytes were used to target B-lymphocytic tumour cells in a standard assay to test chromium release from the B-lymphocytic tumour cells into the medium as an indicator of cell disruption by the murine cytotoxic T-lymphocytes. The latter were exposed through agar bridges to 60-Hz, sinusoidal electric fields for 48 h at intensities of 0.1, 1 and 10 mV/cm in the medium. Following exposure, a 4-h cytotoxicity assay was performed. The results showed a non-significant reduction (7%) in cytotoxicity after exposure to 0.1 mV/cm, and significant reductions of 19% (p p et al., 1998).
The Ames assay using different strains of Salmonella typhimurium (TA100, TA98, TA97a and TA1102) revealed no effect of exposure to ELF magnetic fields (60, 600 and 6000 Hz; 0.3 mT, for 48 h) on mutation frequency (Morandi et al., 1996). Juutilainen and Liimatainen (1986) found no increase of mutation in S. typhimurium strains TA100 and TA98 exposed to 100-Hz magnetic fields (0.13, 1.3 or 130 µT), alone or in combination with the chemical mutagens 4-nitro-ortho-phenylenediamine or sodium azide. Exposure of Chinese hamster cells to ELF magnetic fields for seven days (1 µT; 50 Hz) did not cause a significant increase in the mutation frequency of the Hprt gene encoding the enzyme hypoxanthine-guanine phosphoribosyl transferase (Nafziger et al., 1993). However, exposure of human melanoma MeWo cells to a strong magnetic field (50 Hz, 400 mT) resulted in an increase in the number of mutations of this gene. When the MeWo cells were exposed to the magnetic field in an annular culture plate (diameter, 15 cm), the frequency of HPRT mutations increased from the centre of the plate towards the edge, indicating increased mutation frequency with increasing current density. Under conditions of inhibited DNA synthesis, no induction of mutation was observed. Specifically, there was increased mutation induction during the S phase of the cell cycle (Miyakoshi et al., 1996a, 1997). In a study of exposure of Drosophila melanogaster larvae to an ELF magnetic field (20 mT) using an annular plate, the frequency of somatic mutations increased as a function of induced current (Koana et al., 2001). In a direct examination of the effects of electric fields, a 10-h exposure to a 60-Hz, 10-V/m electric field induced about twice as many Hprt gene mutations as in sham-exposed larvae (Ding et al., 2001). 2ff7e9595c
Комментарии